Research Paper Volume 13, Issue 8 pp 11061—11082

microRNA-363-3p reduces endothelial cell inflammatory responses in coronary heart disease via inactivation of the NOX4-dependent p38 MAPK axis

The protein expression of NOX4 and ratio of p-p38 MAPK/p38 MAPK are upregulated in coronary artery tissues of AS mice. (A) The protein expressions of NOX4, p38 MAPK and p-p38 MAPK were detected by Western blot; (B) Statistical comparison of NOX4, p38 MAPK and p-p38 MAPK protein expressions among four groups; The data were analyzed by one-way ANOVA with Tukey's test; n = 10; * p

Figure 2. The protein expression of NOX4 and ratio of p-p38 MAPK/p38 MAPK are upregulated in coronary artery tissues of AS mice. (A) The protein expressions of NOX4, p38 MAPK and p-p38 MAPK were detected by Western blot; (B) Statistical comparison of NOX4, p38 MAPK and p-p38 MAPK protein expressions among four groups; The data were analyzed by one-way ANOVA with Tukey's test; n = 10; * p < 0.05 vs. the normal group; # p < 0.05 vs. the AS group; AS, atherosclerosis; NOX4, NADPH oxidase 4.