Research Paper Volume 13, Issue 7 pp 9704—9718

Uhrf1 regulates H3K9me2 modification of mTOR to inhibit the effect of autophagy in myocardial ischemia-reperfusion injury

Detection of the changes of Uhrf1 in myocardial ischemia-reperfusion injury model of mice in vivo. The relative mRNA expressions of Uhrf1 in the infarcted and non-infarcted regions of the mice hearts were detected by qRT-PCR at 2, 6 and 12 h after myocardial ischemia-reperfusion injury. Data shown are mean ± SD. * P P P P

Figure 1. Detection of the changes of Uhrf1 in myocardial ischemia-reperfusion injury model of mice in vivo. The relative mRNA expressions of Uhrf1 in the infarcted and non-infarcted regions of the mice hearts were detected by qRT-PCR at 2, 6 and 12 h after myocardial ischemia-reperfusion injury. Data shown are mean ± SD. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001. N=3 per group.