Research Paper Volume 13, Issue 7 pp 9900—9910

LncRNA MNX1-AS1 drives aggressive laryngeal squamous cell carcinoma progression and serves as a ceRNA to target FoxM1 by sponging microRNA-370

MNX1-AS1 was upregulated in LSCC and correlated with poor prognosis. (A) Real-time PCR (qRT-PCR) analysis of MNX1-AS1 expression in 40 primary LSCC tissues and matched adjacent normal tissues. (B) Kaplan-Meier survival curve indicated the high expression of MNX1-AS1 is associated with low survival rates. The median value of MNX1-AS1 expression levels in these LSCC tissues was used to stratify the high and low expression levels of MNX1-AS1. *P **P

Figure 1. MNX1-AS1 was upregulated in LSCC and correlated with poor prognosis. (A) Real-time PCR (qRT-PCR) analysis of MNX1-AS1 expression in 40 primary LSCC tissues and matched adjacent normal tissues. (B) Kaplan-Meier survival curve indicated the high expression of MNX1-AS1 is associated with low survival rates. The median value of MNX1-AS1 expression levels in these LSCC tissues was used to stratify the high and low expression levels of MNX1-AS1. *P < 0.05; **P < 0.01.