Research Paper Volume 13, Issue 7 pp 9911—9926

Exosomes derived from microRNA-512-5p-transfected bone mesenchymal stem cells inhibit glioblastoma progression by targeting JAG1

miR-512-5p is poorly expressed in GBM specimens and cell lines. (A) miR-512-5p expression in glioma tissues from the CCGA database as determined by RT-qPCR. (**p t-test) (B) miR-512-5p expression in non-tumor brain tissues (NBTs) and GBM tissues as detected by FISH (200 ×). (C) miR-512-5p expression in five GBM and NHA cell lines as determined by RT-qPCR. (*p **p

Figure 1. miR-512-5p is poorly expressed in GBM specimens and cell lines. (A) miR-512-5p expression in glioma tissues from the CCGA database as determined by RT-qPCR. (**p < 0.01, Student's t-test) (B) miR-512-5p expression in non-tumor brain tissues (NBTs) and GBM tissues as detected by FISH (200 ×). (C) miR-512-5p expression in five GBM and NHA cell lines as determined by RT-qPCR. (*p < 0.05, **p < 0.01, one-way ANOVA, compared NHA with GBM cell lines). Data are represented as the mean ± standard deviation of three independent experiments.