Research Paper Volume 13, Issue 7 pp 10034—10057

A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients

Schematic representation of study strategy. The flow diagram shows five main sub-sections of this study—(1) bioinformatics analysis of m6A regulatory gene expression; (2) identification of a five-m6A regulatory gene prognostic signature and construction of a prognostic prediction nomogram; (3) external validation using two GEO patient datasets (GSE72094 and GSE41271); (4) WGCNA, and (5) correlation analysis of the prognostic signature with tumor immunity and immunotherapy response.

Figure 10. Schematic representation of study strategy. The flow diagram shows five main sub-sections of this study—(1) bioinformatics analysis of m6A regulatory gene expression; (2) identification of a five-m6A regulatory gene prognostic signature and construction of a prognostic prediction nomogram; (3) external validation using two GEO patient datasets (GSE72094 and GSE41271); (4) WGCNA, and (5) correlation analysis of the prognostic signature with tumor immunity and immunotherapy response.