Research Paper Volume 13, Issue 6 pp 9071—9084

Long non-coding RNA THRIL inhibits miRNA-24-3p to upregulate neuropilin-1 to aggravate cerebral ischemia-reperfusion injury through regulating the nuclear factor κB p65 signaling

LncRNA THRIL is up-regulated in vitro and in vivo models of brain I/R injury. (A) The neurological deficit score. (B) The infract ratio. (C) Fluorescent immunostaining assay was performed in vivo models. (D) RT-qPCR assay detected lncRNA THRIL expression in vivo models. (E) Fluorescent immunostaining assay in vitro model. (F) RT-qPCR assay detected lncRNA THRIL in vitro model. Data are shown as mean ± SD for three-independent experiments. **P

Figure 1. LncRNA THRIL is up-regulated in vitro and in vivo models of brain I/R injury. (A) The neurological deficit score. (B) The infract ratio. (C) Fluorescent immunostaining assay was performed in vivo models. (D) RT-qPCR assay detected lncRNA THRIL expression in vivo models. (E) Fluorescent immunostaining assay in vitro model. (F) RT-qPCR assay detected lncRNA THRIL in vitro model. Data are shown as mean ± SD for three-independent experiments. **P < 0.01.