Research Paper Volume 13, Issue 8 pp 11150—11169

The neuroprotection of deproteinized calf blood extractives injection against Alzheimer's disease via regulation of Nrf-2 signaling

DCBEI improves the behavioral performance of APP/PS1 mice. Compared with non-treated APP/PS1 mice, a 28-day course of DCBEI (A) reduced the escape latency time in the Morris water maze test, (B) decreased the time taken for mice to enter the central area in an open field test. Data are expressed as means ± S.D. (n = 10). # P P P P

Figure 3. DCBEI improves the behavioral performance of APP/PS1 mice. Compared with non-treated APP/PS1 mice, a 28-day course of DCBEI (A) reduced the escape latency time in the Morris water maze test, (B) decreased the time taken for mice to enter the central area in an open field test. Data are expressed as means ± S.D. (n = 10). # P < 0.05 and ## P < 0.01 vs. WT, * P < 0.05 and ** P < 0.01 vs. APP/PS1 mice.