Research Paper Volume 13, Issue 10 pp 13535—13547
FAM134B-mediated endoplasmic reticulum autophagy protects against sepsis myocardial injury in mice
Figure 1. The expression of FAM134B in the mice with sepsis myocardial injury. (A) Mice were divided into four groups: Sham, Sep, Sep + Rap group, and Sep + 3-MA group, and the myocardial histomorphology was examined by H&E staining. (B) Myocardial apoptosis was identified by TUNEL analysis. (C, D) Protein expressions of LC3-II/I (red fluorescence) and FAM134B (green fluorescence) in the myocardial tissues were examined by immunofluorescence and western blot. Data are shown as mean ± SD. *P<0.05, **P<0.01 and ***P<0.001. Sep: Sepsis. SD: standard deviation.