Figure 2. Effect of FAM134B on sepsis myocardial injury in mice. Mice were treated with FAM134B knockdown or overexpression and then with cecal ligation and puncture treatment. Mice were divided into four groups: Sham, Sep, Sep+Rap+siFAM134B, and Sep+3-MA+oeFAM134B. (A) The expression of FAM134B in myocardial tissue was detected by RT-PCR. (B–D) Myocardial tissue morphology and apoptosis were then identified by H&E staining and TUNEL analysis, respectively. Data are shown as mean ± SD. *P<0.05, **P<0.01 and ***P<0.001. Sep: Sepsis. SD: standard deviation.