Research Paper Volume 13, Issue 10 pp 13535—13547

FAM134B-mediated endoplasmic reticulum autophagy protects against sepsis myocardial injury in mice

FAM134B expression was increased in LPS-treated mouse cardiomyocytes. (A) Cardiomyocytes were treated with LPS, or LPS+RAP, or LPS+3-MA. Cell proliferation was examined by CCK8 assay. (B, C) Cell apoptosis was measured by Annexin V/PI staining. (D) The expressions of LC3-II/I and FAM134B were identified by western blot analysis. Data are shown as mean ± SD. *P

Figure 4. FAM134B expression was increased in LPS-treated mouse cardiomyocytes. (A) Cardiomyocytes were treated with LPS, or LPS+RAP, or LPS+3-MA. Cell proliferation was examined by CCK8 assay. (B, C) Cell apoptosis was measured by Annexin V/PI staining. (D) The expressions of LC3-II/I and FAM134B were identified by western blot analysis. Data are shown as mean ± SD. *P<0.05, **P<0.01 and ***P<0.001. SD: standard deviation.