Research Paper Volume 13, Issue 7 pp 10354—10368

Identification of GSPT1 as prognostic biomarker and promoter of malignant colon cancer cell phenotypes via the GSK-3β/CyclinD1 pathway

GSPT1 was increased in colon cancer tissues and cell lines. (A) Expression of GSPT1 in the colon cancer tissues and normal tissues were examined by RT-P assay. (B) The expression level of gspt1 in TCGA database. (C) Immunohistochemistry was used to detect the expression of GSPT1 in normal colon and colon cancer. (D) Expression of GSPT1 in the colon cancer cell lines were examined by RT-P and western blot assay.

Figure 1. GSPT1 was increased in colon cancer tissues and cell lines. (A) Expression of GSPT1 in the colon cancer tissues and normal tissues were examined by RT-P assay. (B) The expression level of gspt1 in TCGA database. (C) Immunohistochemistry was used to detect the expression of GSPT1 in normal colon and colon cancer. (D) Expression of GSPT1 in the colon cancer cell lines were examined by RT-P and western blot assay.