Research Paper Volume 13, Issue 7 pp 10354—10368

Identification of GSPT1 as prognostic biomarker and promoter of malignant colon cancer cell phenotypes via the GSK-3β/CyclinD1 pathway

IP-MS reveal TRIM4 as potential downstream effectors of GSPT1. (A) The specific bands of IP-GSPT1 group and IP normal IgG group were detected by silver staining. (B) The peptide segments of specific bands were detected by mass spectrometry. (C) The fraction of peptide in the mass spectrometry results. (D) Analysis of the interaction between GSPT1 and TRIM4 in colon cancer.

Figure 5. IP-MS reveal TRIM4 as potential downstream effectors of GSPT1. (A) The specific bands of IP-GSPT1 group and IP normal IgG group were detected by silver staining. (B) The peptide segments of specific bands were detected by mass spectrometry. (C) The fraction of peptide in the mass spectrometry results. (D) Analysis of the interaction between GSPT1 and TRIM4 in colon cancer.