Research Paper Volume 13, Issue 7 pp 10354—10368

Identification of GSPT1 as prognostic biomarker and promoter of malignant colon cancer cell phenotypes via the GSK-3β/CyclinD1 pathway

GSPT1 drives the tumorigenicity of colon cells through the GSK3β axis. (A) The gene set enrichment analysis of GSPT1. (B) Correlation analysis of GSPT1 and GSK in TCGA database. (C) GSPT1 negatively regulates GSK-3β signaling pathway. (D) The mechanism of GSPT1 in promoting the occurrence and development of colon cancer.

Figure 6. GSPT1 drives the tumorigenicity of colon cells through the GSK3β axis. (A) The gene set enrichment analysis of GSPT1. (B) Correlation analysis of GSPT1 and GSK in TCGA database. (C) GSPT1 negatively regulates GSK-3β signaling pathway. (D) The mechanism of GSPT1 in promoting the occurrence and development of colon cancer.