Research Paper Volume 13, Issue 8 pp 11507—11527

A novel comprehensive immune-related gene signature as a promising survival predictor for the patients with head and neck squamous cell carcinoma

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Figure 2. The regulatory network of TF and univariate cox analysis of differentially expressed IRGs and OS of HNSCC. (A) The regulatory network constructed based on prognosis-related IRGs and TFs. The red circle represents the high-risk IRGs and the green circular represents the low-risk IRGs. The triangle represents differentially expressed TFs. The red link line represents positive regulation, while there was no observed negative regulation. (B) A total of 24 differentially expressed IRGs found to be significantly associated with the OS of HNSCC patients (p-value < 0.01). Red points represent positive correlations, while green points represent negative correlations.