Figure 5. NET1 overexpression promotes HCC tumorigenesis and intrahepatic metastases in vivo. (A) Left image: representative images of tumors generated by control and NET1-overexpressed Huh7 cells. Middle image: tumor weight (g). Right panel: tumor growth (mm3). (B) Left panel: representative images showing luciferase expression in intrahepatic tumors of mice from control and NET1-overexpressed groups. Right panel: quantification of luciferase expression in intrahepatic tumors. (C) Survival curves of mice in Huh7 control and NET1-overexpressed groups. (D) Representative images of mice livers from Huh7 control and NET1-overexpressed groups with intrahepatic injection. (E) Foci number of injected (left panel) and non-injected (right photograph) lobes of mice with intrahepatic metastasis. All data are presented as mean ± SE. *P < 0.05, **P < 0.01, ***P < 0.001 vs vector cells.