Research Paper Volume 13, Issue 8 pp 11528—11541

MicroRNA-532-5p protects against cerebral ischemia-reperfusion injury by directly targeting CXCL1

MiR-532-5p overexpression significantly inhibited OGD/R-induced inflammation in SH-SY5Y cells. (A–D) ELISA assay results show the levels of (A) IL-1β, (B) TNF-α, (C) IL-6, and (D) MPO in the supernatants of control and miR-532-5p agomir-transfected SH-SY5Y cells treated with or without OGD/R. **P ##P

Figure 3. MiR-532-5p overexpression significantly inhibited OGD/R-induced inflammation in SH-SY5Y cells. (AD) ELISA assay results show the levels of (A) IL-1β, (B) TNF-α, (C) IL-6, and (D) MPO in the supernatants of control and miR-532-5p agomir-transfected SH-SY5Y cells treated with or without OGD/R. **P < 0.01 compared to the control; ##P < 0.01 compared to OGD/R. All experiments were performed in triplicate.