Research Paper Volume 13, Issue 7 pp 10688—10702

Downregulation of OIP5-AS1 affects proNGF-induced pancreatic cancer metastasis by inhibiting p75NTR levels

OIP5-AS1 directly targets miR-186-5p, and miR-186-5p directly targets NGFR. (A, B) Targeted binding site of OIP5-AS1/miR-186-5p and miR-186-5p/NGFR. (C) Level of miR-186-5p after transfection. (D, E) Results of the dual luciferase reporter assay. *P

Figure 3. OIP5-AS1 directly targets miR-186-5p, and miR-186-5p directly targets NGFR. (A, B) Targeted binding site of OIP5-AS1/miR-186-5p and miR-186-5p/NGFR. (C) Level of miR-186-5p after transfection. (D, E) Results of the dual luciferase reporter assay. *P < 0.05 vs. mimic-NC group.