Research Paper Volume 13, Issue 7 pp 10688—10702

Downregulation of OIP5-AS1 affects proNGF-induced pancreatic cancer metastasis by inhibiting p75NTR levels

OIP5-AS1, NGFR and miR-186-5p are associated with prognosis in patients with pancreatic cancer. (A–D) Expression characteristics of OIP5-AS1, miR-186-5p and NGFR in pancreatic cancer patients. (E) Levels of p75NTR protein encoded by NGFR in pancreatic cancer and normal tissues (×100). (F–H) Correlation between the OIP5-AS1, miR-186-5p and NGFR levels. (I–K) Relationship between the OIP5-AS1, miR-186-5p and NGFR levels and survival rate in patients with pancreatic cancer.

Figure 4. OIP5-AS1, NGFR and miR-186-5p are associated with prognosis in patients with pancreatic cancer. (AD) Expression characteristics of OIP5-AS1, miR-186-5p and NGFR in pancreatic cancer patients. (E) Levels of p75NTR protein encoded by NGFR in pancreatic cancer and normal tissues (×100). (FH) Correlation between the OIP5-AS1, miR-186-5p and NGFR levels. (IK) Relationship between the OIP5-AS1, miR-186-5p and NGFR levels and survival rate in patients with pancreatic cancer.