Research Paper Volume 13, Issue 7 pp 10688—10702

Downregulation of OIP5-AS1 affects proNGF-induced pancreatic cancer metastasis by inhibiting p75NTR levels

MiR-186-5p inhibits the migration and invasion of pancreatic cancer by targeting NGFR. (A, B) Levels of NGFR mRNA and p75NTR protein after transfection. (C, D) Comparison of the cell viability in each group. (E, F) Comparison of the migration and invasion abilities of Panc-1 cells in different groups. (G, H) Comparison of the migration and invasion abilities of Capan-1 cells in different groups.

Figure 5. MiR-186-5p inhibits the migration and invasion of pancreatic cancer by targeting NGFR. (A, B) Levels of NGFR mRNA and p75NTR protein after transfection. (C, D) Comparison of the cell viability in each group. (E, F) Comparison of the migration and invasion abilities of Panc-1 cells in different groups. (G, H) Comparison of the migration and invasion abilities of Capan-1 cells in different groups.