Research Paper Volume 13, Issue 8 pp 11564—11594

Comprehensive analysis of genomic and immunological profiles in Chinese and Western hepatocellular carcinoma populations

Characterization of immune cell infiltration and gene mutations in the WCH-HBV-HCC group. (A) Heat map shown the expression of immune cells by IHC staining (Log2 cells/mm2), tumor mutation burden (TMB) and the most common 20 mutation genes in the WCH-HBV-HCC group. (B) Heat map shown the expression of immune cells, TMB and the most common 20 mutation genes based on the TP53 mutation type in the WCH-HBV-HCC group. (C) Heat map shown the TP53 mutation type based on the immune type (HIGH, MIX, and LOW).

Figure 5. Characterization of immune cell infiltration and gene mutations in the WCH-HBV-HCC group. (A) Heat map shown the expression of immune cells by IHC staining (Log2 cells/mm2), tumor mutation burden (TMB) and the most common 20 mutation genes in the WCH-HBV-HCC group. (B) Heat map shown the expression of immune cells, TMB and the most common 20 mutation genes based on the TP53 mutation type in the WCH-HBV-HCC group. (C) Heat map shown the TP53 mutation type based on the immune type (HIGH, MIX, and LOW).