Research Paper Volume 13, Issue 8 pp 11564—11594

Comprehensive analysis of genomic and immunological profiles in Chinese and Western hepatocellular carcinoma populations

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Figure 6. Associations between copy number alterations and ESTIMATE immune score. (A) Pearson correlation of the number of amplified genes and immune scores generated from ESTIMATE for the TCGA-HBV-HCC cohort. (B) Pearson correlation of the number of deleted genes and immune scores for the TCGA-HBV-HCC cohort. (C) Pearson correlation of the number of amplified genes and immune scores for the TCGA-Alcol-HCC cohort. (D) Pearson correlation of the number of deleted genes and immune scores for the TCGA-Alcol-HCC cohort; (E) Boxplot of PTEN copy number levels (in log2 level) in each of the immune infiltrate groups (HIGH, MIX and LOW) for the TCGA-HBV-HCC, WCH-HBV-HCC and TCGA-Alcol-HCC groups.