Research Paper Volume 13, Issue 8 pp 11564—11594

Comprehensive analysis of genomic and immunological profiles in Chinese and Western hepatocellular carcinoma populations

Associations between copy number alterations and ESTIMATE immune score. (A) Pearson correlation of the number of amplified genes and immune scores generated from ESTIMATE for the TCGA-HBV-HCC cohort. (B) Pearson correlation of the number of deleted genes and immune scores for the TCGA-HBV-HCC cohort. (C) Pearson correlation of the number of amplified genes and immune scores for the TCGA-Alcol-HCC cohort. (D) Pearson correlation of the number of deleted genes and immune scores for the TCGA-Alcol-HCC cohort; (E) Boxplot of PTEN copy number levels (in log2 level) in each of the immune infiltrate groups (HIGH, MIX and LOW) for the TCGA-HBV-HCC, WCH-HBV-HCC and TCGA-Alcol-HCC groups.

Figure 6. Associations between copy number alterations and ESTIMATE immune score. (A) Pearson correlation of the number of amplified genes and immune scores generated from ESTIMATE for the TCGA-HBV-HCC cohort. (B) Pearson correlation of the number of deleted genes and immune scores for the TCGA-HBV-HCC cohort. (C) Pearson correlation of the number of amplified genes and immune scores for the TCGA-Alcol-HCC cohort. (D) Pearson correlation of the number of deleted genes and immune scores for the TCGA-Alcol-HCC cohort; (E) Boxplot of PTEN copy number levels (in log2 level) in each of the immune infiltrate groups (HIGH, MIX and LOW) for the TCGA-HBV-HCC, WCH-HBV-HCC and TCGA-Alcol-HCC groups.