Research Paper Volume 13, Issue 8 pp 11629—11645

Circular RNA hsa_circ_0072309 promotes tumorigenesis and invasion by regulating the miR-607/FTO axis in non-small cell lung carcinoma

Hsa

Figure 1. Hsa_circ_0072309 is upregulated in lung adenocarcinoma. (A) Microarray analysis of human lung adenocarcinoma and adjacent normal tissues (n = 5). (B) The expression levels of hsa_circ_0072309, hsa_circ_0000284, hsa_circ_0004873, hsa_circ_0001746 and hsa_circ_0000396 in five pairs of human lung adenocarcinoma and adjacent normal tissues. (C) The expression levels of hsa_circ_0072309, hsa_circ_0000284, hsa_circ_0004873, hsa_circ_0001746 and hsa_circ_0000396 in the human bronchial epithelial cell line HBE and human lung cancer cell lines (A549, H1975 and H1650). One-way ANOVA followed by Tukey’s multiple comparisons test (B). Multiple t-test (C). N.S.: no significance; *p < 0.05, **p < 0.01, ***p < 0.001.