Research Paper Volume 13, Issue 8 pp 11629—11645

Circular RNA hsa_circ_0072309 promotes tumorigenesis and invasion by regulating the miR-607/FTO axis in non-small cell lung carcinoma

The miR-607 inhibitor reversed the suppressed cell proliferation, invasion and migration capability caused by hsa

Figure 5. The miR-607 inhibitor reversed the suppressed cell proliferation, invasion and migration capability caused by hsa_circ_0072309 loss. (A) Cell proliferation assays of control and hsa_circ_0072309-KD H1975 cells with or without miR-607 inhibitor. (B) Transwell assays of control and hsa_circ_0072309-KD H1975 cells with or without miR-607 inhibitor. (C) Wound-healing assays of control and hsa_circ_0072309-KD H1975 cells with or without miR-607 inhibitor. (D) Cell proliferation assays of control and hsa_circ_0072309-KD H1650 cells with or without miR-607 inhibitor. (E) Transwell assays of control and hsa_circ_0072309-KD H1650 cells with or without miR-607 inhibitor. (F) Wound-healing assays of control and hsa_circ_0072309-KD H1650 cells with or without miR-607 inhibitor. Quantitative results are indicated in the right panel (BC, EF). Two-way ANOVA followed by Tukey’s multiple comparisons test. *p < 0.05, **p < 0.01.