Figure 1. Differential expression of SPRY4 and EZH2 between colorectal cancer cells and normal human colon cell. From four human CRC cell lines, SW620, SW480, LOVO and HCT116, and a normal human colon mucosal epithelial cell line NCM460, we detected the mRNA level and protein expression of SPRY4 using western blotting and RT-qPCR, respectively (A–C). The mRNA level and protein expression of EZH2 were detected using western blotting and RT-qPCR, respectively (D–F). **, ***p<0.01, 0.001 vs NCM460.