Research Paper Volume 13, Issue 10 pp 13560—13570

Methylation factor MRPL15 identified as a potential biological target in Alzheimer’s disease

The analysis of DMPs in AD cases and controls. (A) Volcano plot of the top DMPs and position of methylation probes in relation to the gene. The percentages of hypermethylated and hypomethylated DMPs are displayed on top. (B) The proportion of methylation in different chromosomes. (C) Expression of MRPL15 in four datasets. (D) Methylation level of MRPL15.

Figure 5. The analysis of DMPs in AD cases and controls. (A) Volcano plot of the top DMPs and position of methylation probes in relation to the gene. The percentages of hypermethylated and hypomethylated DMPs are displayed on top. (B) The proportion of methylation in different chromosomes. (C) Expression of MRPL15 in four datasets. (D) Methylation level of MRPL15.