Research Paper Volume 13, Issue 8 pp 11727—11737

MiR-27a-3p suppresses cerebral ischemia-reperfusion injury by targeting FOXO1

OGD-induced cell growth inhibition is reversed by miR-27a-3p mimics. (A) FACS analysis of cell apoptosis. (B) The rate of apoptosis among HT22 cells. (C) Western blotting showing levels of active caspase 3, active caspase 9 and Bcl-2 in HT22 cells. (D–F) Relative protein expression levels of active caspase 3 (D), active caspase 9 (E) and Bcl-2 (F) normalizing to GAPDH. **P##P

Figure 2. OGD-induced cell growth inhibition is reversed by miR-27a-3p mimics. (A) FACS analysis of cell apoptosis. (B) The rate of apoptosis among HT22 cells. (C) Western blotting showing levels of active caspase 3, active caspase 9 and Bcl-2 in HT22 cells. (DF) Relative protein expression levels of active caspase 3 (D), active caspase 9 (E) and Bcl-2 (F) normalizing to GAPDH. **P<0.01 vs. control. ##P<0.01 vs. OGD.