Research Paper Volume 13, Issue 8 pp 11727—11737

MiR-27a-3p suppresses cerebral ischemia-reperfusion injury by targeting FOXO1

MiR-27a-3p agomir inhibits the expression of FOXO1, p27 Kip1 and active caspase 3 in brain tissues of rats. (A) Protein levels of FOXO1, p27 Kip1 and active caspase 3 in brain tissue from rats. (B–D) Relative expression levels of FOXO1 (B), p27 Kip1 (C) and active caspase 3 (D) normalized to GAPDH levels. **P##P

Figure 7. MiR-27a-3p agomir inhibits the expression of FOXO1, p27 Kip1 and active caspase 3 in brain tissues of rats. (A) Protein levels of FOXO1, p27 Kip1 and active caspase 3 in brain tissue from rats. (BD) Relative expression levels of FOXO1 (B), p27 Kip1 (C) and active caspase 3 (D) normalized to GAPDH levels. **P<0.01 vs. sham. ##P<0.01 vs. I/R.