Research Paper Volume 13, Issue 8 pp 11808—11821

Exosomes derived from miR-1228 overexpressing bone marrow-mesenchymal stem cells promote growth of gastric cancer cells

Effect of exosomal-miR-1228 derived from BM-MSCs on invasion and migration of gastric cancer cells. (A) After co-culture, the cells transfected with miR-1228-mimics had a decreased invasion, while those transfected with miR-1228-inhibit had an accelerated invasion. (B) After co-culture, the cells transfected with miR-1228-mimics had a decreased migration, while those transfected with miR-1228-inhibit had an accelerated migration. bPvs. miR-NC.

Figure 6. Effect of exosomal-miR-1228 derived from BM-MSCs on invasion and migration of gastric cancer cells. (A) After co-culture, the cells transfected with miR-1228-mimics had a decreased invasion, while those transfected with miR-1228-inhibit had an accelerated invasion. (B) After co-culture, the cells transfected with miR-1228-mimics had a decreased migration, while those transfected with miR-1228-inhibit had an accelerated migration. bP< 0.01 vs. miR-NC.