Figure 3. ITPKA inhibited the tumorigenicity of ovarian cancer. (A) Gross images of the tumors formed by OVCAR3 control cells and OVCAR3/Flag-ITPKA cells in nude mice. (B) Tumor weight as shown in (A). (C) Immunostaining was performed to examine Ki67 expression. (D) Statistical analysis of (C). (E) Expression of P53 and Flag-ITPKA in the tumors was examined via western blot. **P < 0.01.