Research Paper Volume 13, Issue 6 pp 7800—7827

Chronic treatment with acetaminophen protects against liver aging by targeting inflammation and oxidative stress

Analysis of lymphoid populations in liver NPCs from 2 m/o, 14 m/o and 14 m/o + APAP mice by flow cytometry. (A) Percentage of Cd8+ (left) and Cd4+ (right) from Cd45+Cd3+ cells and representative images of flow cytometry analysis. (B) Percentage of Cd8+ (left) and Cd4+ (right) from Cd45+Cd3+NK1.1+ cells and representative images of flow cytometry analysis. Data are represented as the mean ± S.E.M. (n = 14-16 mice per group). Statistical analysis was performed by Brown-Forsythe and Welch ANOVA test followed by their respective post-hoc test. * P P P vs. 2 m/o; #P ##P vs. 14 m/o.

Figure 4. Analysis of lymphoid populations in liver NPCs from 2 m/o, 14 m/o and 14 m/o + APAP mice by flow cytometry. (A) Percentage of Cd8+ (left) and Cd4+ (right) from Cd45+Cd3+ cells and representative images of flow cytometry analysis. (B) Percentage of Cd8+ (left) and Cd4+ (right) from Cd45+Cd3+NK1.1+ cells and representative images of flow cytometry analysis. Data are represented as the mean ± S.E.M. (n = 14-16 mice per group). Statistical analysis was performed by Brown-Forsythe and Welch ANOVA test followed by their respective post-hoc test. * P < 0.05, ** P < 0.01 and *** P < 0.001 vs. 2 m/o; #P < 0.05 and ##P < 0.01 vs. 14 m/o.