Research Paper Volume 13, Issue 10 pp 13615—13625

The effect of IL-6/Piezo2 on the trigeminal neuropathic pain

Immunocytochemistry of IL-6. Immunocytochemistry images of IL-6 in sham group (A) and TN group at different time points (B–F) are demonstrated. The percentage of IL-6 (+) neuron increases at day 3 postoperatively, reaching peak at day 7 (42.4±2.6% in TN group vs. 6.7±1.8% in sham group, pG).

Figure 4. Immunocytochemistry of IL-6. Immunocytochemistry images of IL-6 in sham group (A) and TN group at different time points (BF) are demonstrated. The percentage of IL-6 (+) neuron increases at day 3 postoperatively, reaching peak at day 7 (42.4±2.6% in TN group vs. 6.7±1.8% in sham group, p<0.05) and remaining at a high level up to the last time point of day 21 (G).