Research Paper Volume 13, Issue 9 pp 12466—12478

Supplementary research on K150del variant of activated protein C

Characterization of wild and mutant APC. (A) SDS-PAGE and Coomassie staining of APC-WT and APC-DEL protein samples were performed under non-reducing conditions. (B) Anticoagulant activities of increasing concentrations of APC-WT and APC-DEL. Differences between wild and mutant APC at the same concentration were evaluated (*P P P

Figure 4. Characterization of wild and mutant APC. (A) SDS-PAGE and Coomassie staining of APC-WT and APC-DEL protein samples were performed under non-reducing conditions. (B) Anticoagulant activities of increasing concentrations of APC-WT and APC-DEL. Differences between wild and mutant APC at the same concentration were evaluated (*P < 0.05, **P < 0.01, ***P < 0.001).