Research Paper Volume 13, Issue 8 pp 12067—12085

Expression profile, molecular functions, and prognostic significance of miRNAs in primary colorectal cancer stem cells

A prognostic model based on pCRCSC-related miRNA signature stratifies the OS in CRC patients. The distribution of risk score, overall survival (OS), OS status, and the heat map of prognostic pCRCSC miRNA signature in the training (A, B) validation cohorts. The dotted line indicates the cut-off point of the median risk score used to stratify the patients into low- and high-risk groups. Kaplan–Meier curves of OS for patients with CRC based on pCRCSC-related miRNA signature in the training (C, D) validation cohorts.

Figure 5. A prognostic model based on pCRCSC-related miRNA signature stratifies the OS in CRC patients. The distribution of risk score, overall survival (OS), OS status, and the heat map of prognostic pCRCSC miRNA signature in the training (A, B) validation cohorts. The dotted line indicates the cut-off point of the median risk score used to stratify the patients into low- and high-risk groups. Kaplan–Meier curves of OS for patients with CRC based on pCRCSC-related miRNA signature in the training (C, D) validation cohorts.