Research Paper Volume 13, Issue 8 pp 12086—12098

Interferon regulatory factor transcript levels correlate with clinical outcomes in human glioma

Transcript levels of IRF family members in LGG and GBM (GEPIA). The expression profiles (A) and box plots (B) show that IRF1, IRF2, IRF5, and IRF8 expression were significantly elevated in both LGG and GBM, while IRF7 expression was increased in GBM only. (C) IRF4 and IRF6 are the lowest among all IRFs in both LGG and GBM.

Figure 2. Transcript levels of IRF family members in LGG and GBM (GEPIA). The expression profiles (A) and box plots (B) show that IRF1, IRF2, IRF5, and IRF8 expression were significantly elevated in both LGG and GBM, while IRF7 expression was increased in GBM only. (C) IRF4 and IRF6 are the lowest among all IRFs in both LGG and GBM.