Figure 5. Genetic alterations, co-expression, and interaction analysis of IRF family members in glioma patients. (A) Summary of genetic alterations in IRF family members in glioma. (B) OncoPrint visual summary of alterations in a query of IRF family members (cBioPortal). (C) Kaplan-Meier plot comparing overall survival in cases with/without IRF alterations (cBioPortal). (D) Correlation heat map of differentially expressed IRF family members in glioma (TCGA glioma dataset). (E) Protein-protein interaction network among the nine differentially expressed IRF family members (STRING). (F) Top 20 external genes functionally related to IRF family members and the interaction network (GeneMANIA).