Research Paper Volume 13, Issue 7 pp 9433—9454

Longitudinal normative OCT retinal thickness data for wild-type mice, and characterization of changes in the 3×Tg-AD mice model of Alzheimer's disease

The first row shows inner nuclear layer thickness maps for one WT (mouse E038, two-months-old, right eye) and one 3×Tg-AD (mouse E032, two-months-old, left eye), respectively the left and right maps. The second row shows thickness maps from the outer nuclear layer for the same mouse. The thickness (μm) and p-value are shown per block. Blue/red colors denote thickness below/above the average. Color intensity increases with the increase in the probability of thickness being abnormal.

Figure 5. The first row shows inner nuclear layer thickness maps for one WT (mouse E038, two-months-old, right eye) and one 3×Tg-AD (mouse E032, two-months-old, left eye), respectively the left and right maps. The second row shows thickness maps from the outer nuclear layer for the same mouse. The thickness (μm) and p-value are shown per block. Blue/red colors denote thickness below/above the average. Color intensity increases with the increase in the probability of thickness being abnormal.