Research Paper Volume 13, Issue 9 pp 12493—12513

A novel gene signature for prognosis prediction and chemotherapy response in patients with pancreatic cancer

Functional enrichment and protein-protein interaction (PPI) network analysis. (A–C) Gene ontology (GO) enrichment analysis of resistance-related differentially expressed genes (RRDEGs). (A) Biological process. (B) Cellular component. (C) Molecular function. (D) Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis of RRDEGs. (E) Visualization of the top 25 hub genes in the PPI network. A clustering module with a score of 4.5 is marked with white font. (F) GO enrichment analysis of hub genes in the biological process.

Figure 3. Functional enrichment and protein-protein interaction (PPI) network analysis. (AC) Gene ontology (GO) enrichment analysis of resistance-related differentially expressed genes (RRDEGs). (A) Biological process. (B) Cellular component. (C) Molecular function. (D) Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis of RRDEGs. (E) Visualization of the top 25 hub genes in the PPI network. A clustering module with a score of 4.5 is marked with white font. (F) GO enrichment analysis of hub genes in the biological process.