Research Paper Volume 13, Issue 8 pp 12129—12142

Long noncoding RNA DLGAP1-AS1 promotes the progression of glioma by regulating the miR-1297/EZH2 axis

DLGAP1-AS1 promoted proliferation, migration and invasion in glioma cells by sponging miR-1297 and indirectly regulating EZH2 expression. (A, B) CCK-8 assays showing the proliferative capacity of the glioma cell lines transfected with NC, sh-DLGAP1-AS1 or sh-DLGAP1-AS1 together with miR-1297 inhibitors. (C, D) Colony formation assays showing the proliferative capacity of the glioma cell lines transfected with NC, sh-DLGAP1-AS1 or sh-DLGAP1-AS1 together with miR-1297 inhibitors. (E–H) Transwell assays showing the migration and invasion of the glioma cell lines transfected with NC, sh-DLGAP1-AS1 or sh-DLGAP1-AS1 together with miR-1297 inhibitors. *p

Figure 6. DLGAP1-AS1 promoted proliferation, migration and invasion in glioma cells by sponging miR-1297 and indirectly regulating EZH2 expression. (A, B) CCK-8 assays showing the proliferative capacity of the glioma cell lines transfected with NC, sh-DLGAP1-AS1 or sh-DLGAP1-AS1 together with miR-1297 inhibitors. (C, D) Colony formation assays showing the proliferative capacity of the glioma cell lines transfected with NC, sh-DLGAP1-AS1 or sh-DLGAP1-AS1 together with miR-1297 inhibitors. (EH) Transwell assays showing the migration and invasion of the glioma cell lines transfected with NC, sh-DLGAP1-AS1 or sh-DLGAP1-AS1 together with miR-1297 inhibitors. *p < 0.05, **p < 0.01.