Research Paper Volume 13, Issue 8 pp 12143—12159

Effects of advanced glycation end products on neutrophil migration and aggregation in diabetic wounds

Enzyme-linked immunosorbent assay (ELISA) experiment of rat skin and CCK-8 test of advanced glycation end product (AGE)-stimulated neutrophils. (A) Leukotriene B4 (LTB4) expression in diabetic and control rat skin at different time points after injury. (B) Myeloperoxidase (MPO) expression in diabetic and control rat skin. (C) The results of MPO activity in diabetic and control rat skin. (D) CCK-8 test for neutrophils that were stimulated by AGEs and bovine serum albumin (BSA) for 24 h. *: P

Figure 4. Enzyme-linked immunosorbent assay (ELISA) experiment of rat skin and CCK-8 test of advanced glycation end product (AGE)-stimulated neutrophils. (A) Leukotriene B4 (LTB4) expression in diabetic and control rat skin at different time points after injury. (B) Myeloperoxidase (MPO) expression in diabetic and control rat skin. (C) The results of MPO activity in diabetic and control rat skin. (D) CCK-8 test for neutrophils that were stimulated by AGEs and bovine serum albumin (BSA) for 24 h. *: P<0.05, **: P<0.01, ***: P<0.001. D = days, H = hours.