Research Paper Volume 13, Issue 8 pp 12143—12159

Effects of advanced glycation end products on neutrophil migration and aggregation in diabetic wounds

Results of RNA-SEQ for the differential expression of mRNA between neutrophils that were incubated with advanced glycation end products (AGEs) and neutrophils that were incubated with bovine serum albumin (BSA). (A) Volcano and scatter map of the differentially expressed genes between the two groups. (B) Significantly up- and down-regulated genes between the two groups (P C) Results of Gene Ontology (GO) analysis. Red bars represent BP (biological process), green bars represent CC (cellular component) and blue bars represent MF (molecular function). (D) Results of Gene Set Enrichment Analysis (GSEA) (partial).

Figure 7. Results of RNA-SEQ for the differential expression of mRNA between neutrophils that were incubated with advanced glycation end products (AGEs) and neutrophils that were incubated with bovine serum albumin (BSA). (A) Volcano and scatter map of the differentially expressed genes between the two groups. (B) Significantly up- and down-regulated genes between the two groups (P < 0.05). (C) Results of Gene Ontology (GO) analysis. Red bars represent BP (biological process), green bars represent CC (cellular component) and blue bars represent MF (molecular function). (D) Results of Gene Set Enrichment Analysis (GSEA) (partial).