Research Paper Volume 13, Issue 8 pp 12160—12178

Balasubramide derivative 3C attenuates atherosclerosis in apolipoprotein E-deficient mice: role of AMPK-STAT1-STING signaling pathway

A mechanistic schematic diagram showing Compound 3C alleviates atherosclerosis by multiple mechanisms. Compound 3C improves lipid profile in high-fat diet-fed ApoE-/- mice. Compound 3C is a potent activator of AMPK and inhibit JAK2/STAT1/STING signaling.

Figure 9. A mechanistic schematic diagram showing Compound 3C alleviates atherosclerosis by multiple mechanisms. Compound 3C improves lipid profile in high-fat diet-fed ApoE-/- mice. Compound 3C is a potent activator of AMPK and inhibit JAK2/STAT1/STING signaling.