Research Paper Volume 13, Issue 9 pp 12552—12564

LncRNA NONMMUT055714 acts as the sponge of microRNA-7684-5p to protect against postoperative cognitive dysfunction

Silencing miR-7684-5p restores the effects of silencing NONMMUT055714 in primary hippocampal neurons in vitro. (A) The protein expression of SORLA, Aβ and P-Tau by western blot. (B) The expression of IL-1, IL-6, and TNF-α, as determined by ELISA assay. (C) Silencing miR-7684-5p reverses the effect of si-NONMMUT055714 on markers of oxidative stress. (D) Percentage of hippocampal neuron apoptosis by flow cytometry. N = 3 from three independent experiment. Data represented as mean ± SD; * indicates p

Figure 4. Silencing miR-7684-5p restores the effects of silencing NONMMUT055714 in primary hippocampal neurons in vitro. (A) The protein expression of SORLA, Aβ and P-Tau by western blot. (B) The expression of IL-1, IL-6, and TNF-α, as determined by ELISA assay. (C) Silencing miR-7684-5p reverses the effect of si-NONMMUT055714 on markers of oxidative stress. (D) Percentage of hippocampal neuron apoptosis by flow cytometry. N = 3 from three independent experiment. Data represented as mean ± SD; * indicates p < 0.05.