Research Paper Volume 13, Issue 9 pp 12565—12586

Investigation and verification of the clinical significance and perspective of natural killer group 2 member D ligands in colon adenocarcinoma

Prognostic risk score model and time-dependent ROC curve of ULBP2 gene in COAD and CC RFS and OS based on TCGA cohort and GSE40967 cohort. (A, D) Risk score model plot including risk score ranking, survival status, and heatmaps in COAD in COAD RFS and OS; (B, E) Kaplan–Meier curves for low- and high-risk groups in COAD RFS and OS; (C, F) ROC curves for 1-, 2-, 3-, 4-, and 5-year survival rates from the risk score model in CC RFS and OS; (G and J) Risk score model plot including risk score ranking, survival status, and heatmaps in CC in CC RFS and OS; (H, K) Kaplan–Meier curves for low- and high-risk groups in CC RFS and OS; (I, L) ROC curves for 1-, 2-, 3-, 4-, and 5-year survival rates from the risk score model in CC RFS and OS. Notes: COAD: colon adenocarcinoma; CC: colon cancer; ULBP: unique long 16 (UL16)-binding protein; ROC, receiver operating characteristic; RFS, recurrence-free survival; OS, overall survival.

Figure 3. Prognostic risk score model and time-dependent ROC curve of ULBP2 gene in COAD and CC RFS and OS based on TCGA cohort and GSE40967 cohort. (A, D) Risk score model plot including risk score ranking, survival status, and heatmaps in COAD in COAD RFS and OS; (B, E) Kaplan–Meier curves for low- and high-risk groups in COAD RFS and OS; (C, F) ROC curves for 1-, 2-, 3-, 4-, and 5-year survival rates from the risk score model in CC RFS and OS; (G and J) Risk score model plot including risk score ranking, survival status, and heatmaps in CC in CC RFS and OS; (H, K) Kaplan–Meier curves for low- and high-risk groups in CC RFS and OS; (I, L) ROC curves for 1-, 2-, 3-, 4-, and 5-year survival rates from the risk score model in CC RFS and OS. Notes: COAD: colon adenocarcinoma; CC: colon cancer; ULBP: unique long 16 (UL16)-binding protein; ROC, receiver operating characteristic; RFS, recurrence-free survival; OS, overall survival.