Research Paper Volume 13, Issue 9 pp 12587—12606

Neural presbycusis at ultra-high frequency in aged common marmosets and rhesus monkeys

Effects of age on expression patterns of neuronal and glial markers in marmosets. Confocal immunofluorescence images of cryosections of the modiolus regions of 2-year-old and 12-year-old marmosets. SGNs labeled with TUJ in the (A, A’) 2-year-old and (B, B’) 12-year-old marmosets. MAP2 positive neurons in the modiolus of the (C, C’) 2-year-old and (D, D’) 12-year-old marmosets. GFAP2 positive glia were in the (E, E’) 2-year-old and (F, F’) 12-year-old marmosets. Apoptosis was labelled by cleaved Caspase-3 in 2-year-old marmoset (G, G’) and 12-year-old marmoset (H, H’). Scale bar: 50 μm.

Figure 5. Effects of age on expression patterns of neuronal and glial markers in marmosets. Confocal immunofluorescence images of cryosections of the modiolus regions of 2-year-old and 12-year-old marmosets. SGNs labeled with TUJ in the (A, A’) 2-year-old and (B, B’) 12-year-old marmosets. MAP2 positive neurons in the modiolus of the (C, C’) 2-year-old and (D, D’) 12-year-old marmosets. GFAP2 positive glia were in the (E, E’) 2-year-old and (F, F’) 12-year-old marmosets. Apoptosis was labelled by cleaved Caspase-3 in 2-year-old marmoset (G, G’) and 12-year-old marmoset (H, H’). Scale bar: 50 μm.