Research Paper Volume 13, Issue 9 pp 12607—12630

Construction and topological analysis of an endometriosis-related exosomal circRNA-miRNA-mRNA regulatory network

Functional enrichment analysis of DEMs. (A–C) The top 5 C5 GO biological processes and top 5 C2 KEGG pathways enriched in the DEMs between the EC and Ctrl groups (A), the EU and Ctrl groups (B) and the EC and EU groups (C) in the GSEA. The six most common functional gene sets in endometriosis are shown. (D, E) GO and KEGG pathway analyses of the overlapping upregulated DEMs (D) and downregulated DEMs (E) among the three comparison sets. GO: Gene ontology. BP: Biological process. KEGG: Kyoto Encyclopedia of Genes and Genomes.

Figure 3. Functional enrichment analysis of DEMs. (AC) The top 5 C5 GO biological processes and top 5 C2 KEGG pathways enriched in the DEMs between the EC and Ctrl groups (A), the EU and Ctrl groups (B) and the EC and EU groups (C) in the GSEA. The six most common functional gene sets in endometriosis are shown. (D, E) GO and KEGG pathway analyses of the overlapping upregulated DEMs (D) and downregulated DEMs (E) among the three comparison sets. GO: Gene ontology. BP: Biological process. KEGG: Kyoto Encyclopedia of Genes and Genomes.