Research Paper Volume 13, Issue 9 pp 12631—12640

Bioinformatics analysis of the molecular mechanism of obesity in polycystic ovary syndrome

The DGEs special for obesity in PCOS. (A) The expression pattern of the 8 detected DGEs in GSE98421. (B) The expression of the gene CHRDL1 was found to be in linear regression with the BMI index in PCOS patients (p = 0.0358, Y = 6.460*X - 17.51). (C) The expression of CHRDL 1 was significantly higher in obesity PCOS cases than the BMI matched healthy controls (p = 0.0415). (D) There was no statistical difference of CHRDL1 expression between the obesity and normal cases.

Figure 3. The DGEs special for obesity in PCOS. (A) The expression pattern of the 8 detected DGEs in GSE98421. (B) The expression of the gene CHRDL1 was found to be in linear regression with the BMI index in PCOS patients (p = 0.0358, Y = 6.460*X - 17.51). (C) The expression of CHRDL 1 was significantly higher in obesity PCOS cases than the BMI matched healthy controls (p = 0.0415). (D) There was no statistical difference of CHRDL1 expression between the obesity and normal cases.