Figure 4. Immune microenvironment and genomic features in relation to 2 HCC subtypes. Distinct enrichment of (A) infiltration immune cells, (B) immune-related signatures, and (C) immune checkpoints in the 2 HCC subtypes. (D) The association of 2 identified subtypes with TML. (E) Forest plot representation of the association between the 2 identified subtypes and TML. * P < 0.05, ** P < 0.01, *** P < 0.001.