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Advance Publications

Age-related diseases as a testbed for anti-aging therapeutics: the case of idiopathic pulmonary fibrosis

Alex Zhavoronkov, Dominika Wilczok, Feng Ren, Fedor Galkin,
https://doi.org/10.18632/aging.206301
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Analysis of the current state of frailty indexes and their implementation for aging intervention studies

Oliver G. Frost, Anna Barkovskaya, Michael J. Rae, Marcela Atzori, Abdelhadi Rebbaa, Amit Sharma,
https://doi.org/10.18632/aging.206307
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Research Papers

Exosomes released from senescent cells and circulatory exosomes isolated from human plasma reveal aging-associated proteomic and lipid signatures

Sandip Kumar Patel, Joanna Bons, Jacob P. Rose, Jessie R. Chappel, Rebecca L. Beres, Mark A. Watson, Corey Webster, Jordan B. Burton, Roland Bruderer, Pierre-Yves Desprez, Lukas Reiter, Judith Campisi, Erin S. Baker, Birgit Schilling,
https://doi.org/10.18632/aging.206292
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Causal relationships between gut microbiome and hundreds of age-related traits: evidence of a replicable effect on ApoM protein levels

Federica Grosso, Daniela Zanetti, Serena Sanna,
https://doi.org/10.18632/aging.206293
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Models for age-specific estimation of appendicular skeletal muscle mass using the ultrasound-measured rectus femoris muscle thickness

Ga Yang Shim, Jong Bum Kim, Chang Won Won, Jae-Young Lim,
https://doi.org/10.18632/aging.206294
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AI-driven toolset for IPF and aging research associates lung fibrosis with accelerated aging

Fedor Galkin, Shan Chen, Alex Aliper, Alex Zhavoronkov, Feng Ren,
https://doi.org/10.18632/aging.206295
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Age-related trends in amyloid positivity in Parkinson’s disease without dementia

Keiko Hatano, Masashi Kameyama, Masanori Kurihara, Kensuke Ohse, Ryoji Goto, Ryoko Ihara, Mana Higashihara, Renpei Sengoku, Yasushi Nishina, Kazutomi Kanemaru, Yuko Saito, Shigeo Murayama, Atsushi Iwata,
https://doi.org/10.18632/aging.206297
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The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity

Abhishek Guha, Ying Si, Reed Smith, Brijesh K. Singh, Benisa Zogu, Angad Yadav, Katherine A. Smith, Mohamed Kazamel, Nan Jiang, Ritchie Ho, Anna Thalacker-Mercer, Shaida A. Andrabi, Joao D. Tavares Da Silva Pereira, Juliana S. Salgado, Manasi Agrawal, Emina Horvat Velic, Peter H. King,
https://doi.org/10.18632/aging.206298
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Senescent cell heterogeneity and responses to senolytic treatment are related to cell cycle status during senescence induction

Francesco Neri, Shuyuan Zheng, Mark A. Watson, Pierre-Yves Desprez, Akos A. Gerencser, Judith Campisi, Denis Wirtz, Pei-Hsun Wu, Birgit Schilling,
https://doi.org/10.18632/aging.206299
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What is the clinical evidence to support off-label rapamycin therapy in healthy adults?

Jacob M. Hands, Michael S. Lustgarten, Leigh A. Frame, Bradley Rosen,
https://doi.org/10.18632/aging.206300
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Blood vessel and osteocyte networks concurrently rearrange during bone maturation and decline during aging in the femur of male mice

Mathilde Palmier, Marlène Maître, Hélène Doat, Thierry Lesté-Lasserre, Claudine Boiziau, Delphine B. Maurel,
https://doi.org/10.18632/aging.206302
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DNMT1-mediated SPINT2 expression drives early senescence by suppressing c-Met signaling in human fibroblasts

Min Seok Sim, Hae-Ok Byun, Seongki Min, Jiwon Hong, Su Bin Lim, Kyoung Sook Choi, Gyesoon Yoon,
https://doi.org/10.18632/aging.206303
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Sex-specific longitudinal reversal of aging in old frail mice

Cameron Kato, Jessica Zheng, Cindy Quang, Sophia Siopack, Joana Cruz, Zachery R. Robinson, Nicole Fong, Zhixin A. Zhang, Patrick Young, Michael J. Conboy, Irina M. Conboy,
https://doi.org/10.18632/aging.206304
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Evaluating the nonlinear effects of sleep duration on biological aging across phenotypic, genomic, and epigenomic data

Xueyao Wu, Xunying Zhao, Aaron Ge, Zhitong Han, Can Hou, Yu Hao, Jinyu Xiao, Mengyu Fan, Stephen Burgess, Jiayuan Li, Xia Jiang,
https://doi.org/10.18632/aging.206306
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Longitudinal relationship between social and CVD risk factors in older adults with prediabetes: the HRS 2006-2016

Obinna Ekwunife, Yilin Xu, Raphael Fraser, Jennifer Campbell, Rebekah J. Walker, David Jacobs, Leonard E. Egede,
https://doi.org/10.18632/aging.206308
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Deregulated miR-145 and miR-27b in hutchinson-gilford progeria syndrome: implications for adipogenesis

Felix Quirin Fenzl, Eva-Maria Lederer, Louisa Brumma, Peter Krüger, Moritz Schroll, Frederic Wilming, Karima Djabali,
https://doi.org/10.18632/aging.206309
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The impact of long-term social housing on biconditional association task performance and neuron ensembles in the anterior cingulate cortex and the hippocampal CA3 region of aged rats

Anne M. Dankert, Abbi R. Hernandez, Taylor B. Wise, Katrina I. T. Dayaw, Judith N. T. Dayaw, Rachael M. Layden, Katelyn N. Lubke, Sara N. Burke, Victoria L. Templer,
https://doi.org/10.18632/aging.206310
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A protective role of SRC-1 against aging associated cognitive decline

Hesong Liu, Yongjie Yang, Jonathan C. Bean, Yang He, Hailan Liu, Rambabu Majji, Chen Liang, Nan Zhang, Meng Yu, Longlong Tu, Qingzhuo Liu, Yue Deng, Kristine M. Conde, Na Yin, Mengjie Wang, Yongxiang Li, Junying Han, Sanika Vattakuzhiyil Jossy, Megan Elyse Burt, Hari Krishna Yalamanchili, Chunmei Wang,
https://doi.org/10.18632/aging.206311
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Bleomycin promotes cellular senescence and activation of the cGAS-STING pathway without direct effect on fibrosis in an idiopathic pulmonary fibrosis model

Yoko Miura, Nadia Milad, Akiho Takata, Satoshi Kanazawa,
https://doi.org/10.18632/aging.206312
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RGC32 promotes the progression of ccRCC by activating the NF-κB/SHP2/EGFR signaling pathway

Jing Zhang, Yindi Sun, Kai Tang, Huirong Xu, Junjuan Xiao, Yan Li,
https://doi.org/10.18632/aging.205890
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CCNA2 and KIF23 are molecular targets for the prognosis of adenoid cystic carcinoma

Yongbin Di, Haolei Zhang, Bohao Zhang, Tianke Li, Dan Li,
https://doi.org/10.18632/aging.205703
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Identification of an immune subtype predicting survival risk and immune activity in hepatocellular carcinoma

Feng Zhao, Nuo Xu, Jiali Yang, Bo Li, Jianwei Shi, Yuanyuan Zheng, Longjin Xu,
https://doi.org/10.18632/aging.202953
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Reviews

Getting to the heart of sarcopenia and cardiovascular disease

Pouya Nezafati, Pankaj Saxena, Jaishankar Raman, Lionel Hebbard, Craig McFarlane,
https://doi.org/10.18632/aging.206296
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Mitochondrial proteins as biomarkers of cellular senescence and age-associated diseases

Anna Panfilova, Tatiana Zubareva, Ekaterina Mironova, Gianluigi Mazzoccoli, Maria Greta Pia Marasco, Sofya Balazovskaia, Peter Yablonsky, Igor Kvetnoy,
https://doi.org/10.18632/aging.206305
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