Research Paper Volume 13, Issue 9 pp 12849—12864

The prognostic and immunological effects of ZBTB7C across cancers: friend or foe?

ZBTB7C and immune infiltration in colorectal cancer. (A) The top seven immune-infiltrating cells with the strongest correlation with ZBTB7C. (B–C) The correlation between (B) B cells and (C) mast cells and ZBTB7C using the ssGSEA method. (D–E) Differential expression of (D) mast cells and (E) B cells in colorectal cancer and adjacent tissues. (F–K) The differential expression of ZBTB7C in (F) the high and low infiltration groups, (I) left and right colorectal cancers, and (K) mutant and wild type TP53. (G, H) The correlation between ZBTB7C and immune markers in the (G) GEO and (H) TCGA databases. (L, M) Based on the TIMER database, the correlation between ZBTB7C and mast cells and B cells in (L) colon adenocarcinoma (COAD) and (M) rectal adenocarcinoma (READ).

Figure 5. ZBTB7C and immune infiltration in colorectal cancer. (A) The top seven immune-infiltrating cells with the strongest correlation with ZBTB7C. (BC) The correlation between (B) B cells and (C) mast cells and ZBTB7C using the ssGSEA method. (DE) Differential expression of (D) mast cells and (E) B cells in colorectal cancer and adjacent tissues. (FK) The differential expression of ZBTB7C in (F) the high and low infiltration groups, (I) left and right colorectal cancers, and (K) mutant and wild type TP53. (G, H) The correlation between ZBTB7C and immune markers in the (G) GEO and (H) TCGA databases. (L, M) Based on the TIMER database, the correlation between ZBTB7C and mast cells and B cells in (L) colon adenocarcinoma (COAD) and (M) rectal adenocarcinoma (READ).