Research Paper Volume 13, Issue 8 pp 10955—10972

Hyperbaric oxygen therapy effectively alleviates D-galactose-induced-age-related cardiac dysfunction via attenuating mitochondrial dysfunction in pre-diabetic rats

Effect of HBOT on senescence marker expression in left ventricular cardiomyocytes of pre-diabetic rats after induction of aging by D-gal. (A) Result of SA-β-gal staining. (B) Representative figures of SA-β-gal staining. NDV, normal diet fed rats with vehicle; NDDg, normal diet fed rats with D-gal; HFV, high-fat diet fed rats with vehicle; HFDg, high-fat diet fed rats with D-gal; SA-β-gal, senescence associated β galactosidase; HBOT, hyperbaric oxygen therapy. (n = 3/group). *P

Figure 1. Effect of HBOT on senescence marker expression in left ventricular cardiomyocytes of pre-diabetic rats after induction of aging by D-gal. (A) Result of SA-β-gal staining. (B) Representative figures of SA-β-gal staining. NDV, normal diet fed rats with vehicle; NDDg, normal diet fed rats with D-gal; HFV, high-fat diet fed rats with vehicle; HFDg, high-fat diet fed rats with D-gal; SA-β-gal, senescence associated β galactosidase; HBOT, hyperbaric oxygen therapy. (n = 3/group). *P < 0.05.